ABSTRACT
@EN Myasthenia gravis (MG) is a neuromuscular transmission disorder characterized by fatigue and weakness of voluntary muscles. This muscular weakness is intensified by activity and stress, and improved by the use of anticholinesterase compounds.
The
pathogenesis is known to be an autoimmune related reduction in the number of available acetylcholine receptors at neuromuscular junction. Myasthenia gravis is usually associated with other autoimmune disorders, such as autoimmune thyroid disease,
rheumatoid arthritis, SLE, pernicious anemia, Sjogrens syndrome, ulcerative colitis, Eaton-Lambert syndrome. In the past reports, there were some cases of hyperthyroidism associated with myasthenia gravis. But, hypothyroidism accompaning
myasthenia
gravis was reported rarely. So, we report a case of myasthenia gravis associated with Hypothyroidism may be due to Hashimoto's thyroiditis. (J Kor Soc Endocrinol 8:217~220, 1993)
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